LOPERAMIDE

Loperamide Adverse Events Reported to the FDA Over Time

How are Loperamide adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Loperamide, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Loperamide is flagged as the suspect drug causing the adverse event.

Most Common Loperamide Adverse Events Reported to the FDA

What are the most common Loperamide adverse events reported to the FDA?

Diarrhoea	255 (3.47%)
Overdose	146 (1.98%)
Drug Ineffective	129 (1.75%)
Vomiting	117 (1.59%)
Constipation	106 (1.44%)
Haematochezia	100 (1.36%)
Drug Interaction	93 (1.26%)
Abdominal Pain	87 (1.18%)
Intentional Drug Misuse	71 (.97%)
Dehydration	70 (.95%)
Dyspnoea	68 (.92%)
	Show More
Nausea	67 (.91%)
Somnolence	66 (.9%)
Suicide Attempt	63 (.86%)
Pyrexia	62 (.84%)
Incorrect Dose Administered	56 (.76%)
Weight Decreased	54 (.73%)
Abdominal Distension	50 (.68%)
Abdominal Pain Upper	49 (.67%)
Dizziness	49 (.67%)
Intestinal Obstruction	47 (.64%)
Malaise	45 (.61%)
Rash	45 (.61%)
Toxic Epidermal Necrolysis	45 (.61%)
Loss Of Consciousness	44 (.6%)
Fatigue	43 (.58%)
Multiple Drug Overdose Intentional	41 (.56%)
Renal Failure Acute	39 (.53%)
Death	38 (.52%)
Asthenia	37 (.5%)
Urinary Retention	37 (.5%)
Completed Suicide	35 (.48%)
International Normalised Ratio Incr...	34 (.46%)
Renal Failure	34 (.46%)
Faeces Discoloured	33 (.45%)
Thrombocytopenia	33 (.45%)
Rectal Haemorrhage	32 (.44%)
Anaemia	31 (.42%)
Chest Pain	31 (.42%)
Ileus	30 (.41%)
Intentional Overdose	30 (.41%)
Anxiety	29 (.39%)
Confusional State	29 (.39%)
Expired Drug Administered	29 (.39%)
Fall	29 (.39%)
Product Quality Issue	29 (.39%)
Stevens-johnson Syndrome	28 (.38%)
Hyponatraemia	27 (.37%)
Pain	27 (.37%)
Syncope	27 (.37%)
Inappropriate Schedule Of Drug Admi...	26 (.35%)
Sepsis	26 (.35%)
Tachycardia	26 (.35%)
Blood Glucose Increased	25 (.34%)
Cholestasis	25 (.34%)
Decreased Appetite	25 (.34%)
Haemorrhage	25 (.34%)
Multiple Drug Overdose	25 (.34%)
Pruritus	25 (.34%)
Urticaria	25 (.34%)
Choking	24 (.33%)
Hypotension	24 (.33%)
Wrong Technique In Drug Usage Proce...	24 (.33%)
Anaphylactic Reaction	23 (.31%)
Dysphagia	23 (.31%)
Headache	23 (.31%)
Heart Rate Increased	23 (.31%)
Muscle Spasms	23 (.31%)
Septic Shock	23 (.31%)
Colitis Ischaemic	22 (.3%)
Faecaloma	22 (.3%)
Gastrointestinal Disorder	22 (.3%)
Abdominal Discomfort	21 (.29%)
Agitation	21 (.29%)
Condition Aggravated	21 (.29%)
Drug Abuse	21 (.29%)
Dysuria	21 (.29%)
Haemoglobin Decreased	21 (.29%)
Incorrect Drug Administration Durat...	21 (.29%)
Megacolon	21 (.29%)
Suicidal Ideation	21 (.29%)
Coma	20 (.27%)
Drug Exposure During Pregnancy	20 (.27%)
Leukopenia	20 (.27%)
Neutropenia	20 (.27%)
Alanine Aminotransferase Increased	19 (.26%)
Cardiac Arrest	19 (.26%)
Drug Dependence	19 (.26%)
Flatulence	19 (.26%)
Hypersensitivity	19 (.26%)
Pain In Extremity	19 (.26%)
Anaphylactic Shock	18 (.24%)
Contusion	18 (.24%)
Cytolytic Hepatitis	18 (.24%)
Depressed Level Of Consciousness	18 (.24%)
Drug Toxicity	18 (.24%)
Gamma-glutamyltransferase Increased	18 (.24%)
Oedema Peripheral	18 (.24%)
Atrial Fibrillation	17 (.23%)
Cholelithiasis	17 (.23%)
Dry Mouth	17 (.23%)

Share/Embed Graph Export Data

This graph shows the top adverse events submitted to the FDA for Loperamide, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Loperamide is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Loperamide

What are the most common Loperamide adverse events reported to the FDA?

Gastrointestinal Signs	530 (7.21%)
Gastrointestinal Motility And Defec...	466 (6.33%)
Medication Errors	453 (6.16%)
Neurological	343 (4.66%)
Therapeutic And Nontherapeutic Effe...	281 (3.82%)
Epidermal And Dermal Conditions	272 (3.7%)
Respiratory	242 (3.29%)
Hepatic And Hepatobiliary	154 (2.09%)
Gastrointestinal Hemorrhages	149 (2.03%)
Electrolyte And Fluid Balance Condi...	147 (2%)
Infections - Pathogen Unspecified	140 (1.9%)
	Show More
Psychiatric	137 (1.86%)
Suicidal And Self-injurious Behavio...	127 (1.73%)
Cardiac Arrhythmias	123 (1.67%)
Gastrointestinal Stenosis And Obstr...	118 (1.6%)
Hematology Investigations	118 (1.6%)
Urinary Tract Signs	104 (1.41%)
Injuries	100 (1.36%)
Renal Disorders	99 (1.35%)
Hepatobiliary	88 (1.2%)
Physical Examination Topics	85 (1.16%)
White Blood Cell	77 (1.05%)
Body Temperature Conditions	74 (1.01%)
Product Quality Issues	73 (.99%)
Cardiac And Vascular Investigations	68 (.92%)
Allergic Conditions	67 (.91%)
Gastrointestinal Ulceration And Per...	62 (.84%)
Anxiety Disorders	61 (.83%)
Appetite And General Nutritional	54 (.73%)
Chemical Injury And Poisoning	54 (.73%)
Metabolic, Nutritional And Blood Ga...	51 (.69%)
Muscle	50 (.68%)
Deliria	49 (.67%)
Oral Soft Tissue Conditions	49 (.67%)
Gastrointestinal Inflammatory Condi...	48 (.65%)
Anemias Nonhemolytic And Marrow Dep...	46 (.63%)
Bacterial Infectious	46 (.63%)
Neuromuscular	45 (.61%)
Movement Disorders	44 (.6%)
Ocular Infections, Irritations And ...	42 (.57%)
Gastrointestinal Conditions	40 (.54%)
Musculoskeletal And Connective Tiss...	40 (.54%)
Lower Respiratory Tract Disorders	39 (.53%)
Vascular Hemorrhagic	39 (.53%)
Fatal Outcomes	38 (.52%)
Water, Electrolyte And Mineral	34 (.46%)
Platelet	33 (.45%)
Decreased And Nonspecific Blood Pre...	32 (.44%)
Lifestyle Issues	32 (.44%)
Angiedema And Urticaria	31 (.42%)
Cardiac Disorder Signs	28 (.38%)
Ocular Neuromuscular	27 (.37%)
Enzyme	26 (.35%)
Coronary Artery	25 (.34%)
Gastrointestinal Vascular Condition...	24 (.33%)
Headaches	24 (.33%)
Upper Respiratory Tract Disorders	24 (.33%)
Viral Infectious	24 (.33%)
Joint	23 (.31%)
Vascular Hypertensive	23 (.31%)
Vision	23 (.31%)
Central Nervous System Vascular	22 (.3%)
Depressed Mood Disorders	22 (.3%)
Neonatal And Perinatal Conditions	22 (.3%)
Renal And Urinary Tract Investigati...	22 (.3%)
Vascular	22 (.3%)
Bronchial Disorders	21 (.29%)
Heart Failures	21 (.29%)
Protein And Chemistry Analyses	21 (.29%)
Bone And Joint Injuries	20 (.27%)
Tongue Conditions	20 (.27%)
Encephalopathies	19 (.26%)
Exocrine Pancreas Conditions	19 (.26%)
Protein And Amino Acid Metabolism	19 (.26%)
Spleen, Lymphatic And Reticulendoth...	19 (.26%)
Acid-base	18 (.24%)
Gallbladder	18 (.24%)
Increased Intracranial Pressure And...	18 (.24%)
Mental Impairment	18 (.24%)
Peritoneal And Retroperitoneal Cond...	18 (.24%)
Seizures	18 (.24%)
Skin Vascular Abnormalities	18 (.24%)
Anal And Rectal Conditions	17 (.23%)
Disturbances In Thinking	17 (.23%)
Salivary Gland Conditions	17 (.23%)
Skin Appendage Conditions	17 (.23%)
Mood Disorders	16 (.22%)
Eye	15 (.2%)
Arteriosclerosis, Stenosis, Vascula...	14 (.19%)
Inner Ear And Viiith Cranial Nerve	14 (.19%)
Toxicology And Therapeutic Drug Mon...	14 (.19%)
Gastrointestinal	13 (.18%)
Pulmonary Vascular	13 (.18%)
Bone, Calcium, Magnesium And Phosph...	12 (.16%)
Glucose Metabolism Disorders	12 (.16%)
Sleep Disorders	12 (.16%)
Therapeutic Procedures And Supporti...	12 (.16%)
Peripheral Neuropathies	11 (.15%)
Personality Disorders	11 (.15%)
Skin And Subcutaneous Tissue	11 (.15%)
Coagulopathies And Bleeding Diathes...	10 (.14%)

Share/Embed Graph Export Data

This graph shows the top categories of adverse events submitted to the FDA for Loperamide, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Loperamide is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.